We have been using Reply Manager for a couple of years and have found it to be a valuable piece of software.
All the messages from all our selling channels (eBay, Amazon, CDiscount, Fruugo, Game, Rakuten, websites and imap / pop3 email addresses) come through to one control panel. No more logging in to different channels to check messages.
Common replies can be set up to make life easier, and auto-responders are available.
The system also links up to our Linnworks package as well, so a quick click on the Linnworks link in a message brings that order up without the need to search on Linnworks.
The system is really easy to set up, and in the time we have been using the system we have only contacted customer service once, and our enquiry was dealt with swiftly.
If you are selling across multiple channels, then this software can save you loads of time and effort and is therefore, in my opinion, well worth the money..
E-commerce , love it or hate it, that's why we are here